Utilising advanced tools, accurate observations and absolute logic, the mysterious becomes discernable and the discernable, in turn, becomes actionable. Find a problem. Fix a problem.
Tonight, we ask science to take a cue from a bouncing red ball, a small red ball. Focus and faculty are requested. We will paint a blue 50V on one small, red bouncing ball and then see where it goes. If the results are plausible, we may try another.
Follow that springy, red ball from one continent to the next. And then back again.
The ΣPF11 influenza reservoir is not mysterious in the least when the data that has been collected is actually made available for evaluation. Even post-pandemic publications may be informative. We come to some such encounter today from a recent post-pandemic deposit of pandemic H1N1 sequences from England.
Watch the RnR * polymorphisms choose backgrounds and associate with other revisions as this Enhanced Acquisition virus becomes something new everyday in every city around the globe. Humans, swine and birds are vectors, but only humans and birds can fly. Swine store; humans and birds promote.
Let the following sequences describe the arc of two individual silent changes between and among India, the United Kingdom and the United States of America, including military personnel. Synonymous 50V and synonymous 348V are only two examples. These two representatives are certainly not comprehensive of this interchange behaviour.
. . . . England94840759_2009_11 (
. . . . . . . . syn50V [GDWujiang51_2010_03_18,
. . . . . . . . . . . . . . SouthCarolina02E3_2010_03_05
. . . . . . . . . . . . . . . . . . . . . . with 25R,
. . . . . . . . . . . . . . TexasJMS413_2010_02_03
. . . . . . . . . . . . . . . . . . . . . . with 25R,
. . . . . . . . . . . . . . TexasJMS391_2009_12_23
. . . . . . . . . . . . . . . . . . . . . . with 25R,
. . . . . . . . . . . . . . IndiaPune10604_2009_09],
. . . . . . . . 214R,
. . . . . . . . syn428L)
. . . . England734_2009_10 (
. . . . . . . . syn50V [GDWujiang51_2010_03_18,
. . . . . . . . . . . . . . SouthCarolina02E3_2010_03_05
. . . . . . . . . . . . . . . . . . . . . . with 25R,
. . . . . . . . . . . . . . TexasJMS413_2010_02_03
. . . . . . . . . . . . . . . . . . . . . . with 25R,
. . . . . . . . . . . . . . TexasJMS391_2009_12_23
. . . . . . . . . . . . . . . . . . . . . . with 25R,
. . . . . . . . . . . . . . IndiaPune10604_2009_09])
. . . . Eng662_2009_08 (
. . . . . . . . 25R [SouthCarolina02E3_2010_03_05
. . . . . . . . . . . . . . . .. . . . with syn50V,
. . . . . . . . . . . TexasJMS413_2010_02_03
. . . . . . . . . . . . . . . .. . . . with syn50V,
. . . . . . . . . . . TexasJMS391_2009_12_23
. . . . . . . . . . . . . . . .. . . . with syn50V,
. . . . . . . . . . . Texas extensive (10 more),
. . . . . . . . . . . Afghanistan (2),
. . . . . . . . . . . Russia149_2009_11_01_xL,
. . . . . . . . . . . Utah42_2009_07_24
. . . . . . . . . . . . . . . with 225G / 225N],
. . . . . . . . syn116R [NY6530_2010_02_21,
. . . . . . . . . . . . . . swOsaka1_2009_10,
. . . . . . . . . . . . . . Texas45071344_2009_09_07,
. . . . . . . . . . . . . . Portugal (2) 2009_08_19,
. . . . . . . . . . . . . . Military (30) 2009_08 to 2009_12,
. . . . . . . . . . . . . . Australia as early as 2009_07 (3),
. . . . . . . . . . . . . . SingTLL53_2009_06_14,
. . . . . . . . . . . . . . Columbia 2009_06 (2),
. . . . . . . . . . . . . . WiscD1606_2009_05_03],
. . . . . . . . syn348V [JapanAF2284_2009_11_27,
. . . . . . . . . . . . . . Frankfurt301_2009_11_23,
. . . . . . . . . . . . . . Ankara27_2009_11_11,
. . . . . . . . . . . . . . Yaroslavl_CHMV_2009_11_10_f with 225G,
. . . . . . . . . . . . . . Yakutsk_EAV_2009_11_18,
. . . . . . . . . . . . . . Thailand (24) as late as 2009_09_25,
. . . . . . . . . . . . . . BZ_SaoPaulo53823_2009_08_01_f,
. . . . . . . . . . . . . . Yakutsk_EAV_2009_11_18,
. . . . . . . . . . . . . . IndiaPune6196_2009_08,
. . . . . . . . . . . . . . IndiaDhule9433_2009_08,
. . . . . . . . . . . . . . IndiaPune807_2009_07,
. . . . . . . . . . . . . . PNG_PortMoresby2005_2009_07_08,
. . . . . . . . . . . . . . MoroccoRabat72_2009_07_02,
. . . . . . . . . . . . . . Slovenia2322_2009_07_01,
. . . . . . . . . . . . . . SingON442_2009_06_25,
. . . . . . . . . . . . . . ThailandCUB5_2009_06_13],
. . . . . . . . 494K [Indiana21_2009_12_10,
. . . . . . . . . . . . NewMexico07_2009_10_18,
. . . . . . . . . . . . NY5755_2009_10_01,
. . . . . . . . . . . . Ankara12_2009_09,
. . . . . . . . . . . . Ankara16_2009_09,
. . . . . . . . . . . . Ankara29_2009,
. . . . . . . . . . . . NY4568_2009_07_09,
. . . . . . . . . . . . NY4500_2009_07_01,
. . . . . . . . . . . . RhodeIsland04_2009_06_01])
Three American sequences are on file from December 2009 to March 2010 that accumulate both the 25R of Eng662_2009_08 and the syn50V of IndiaPune10604_2009_09. A pattern of attraction or permissiveness is suggested.
- SouthCarolina02E3_2010_03_05
- TexasJMS413_2010_02_03
- TexasJMS391_2009_12_23
India is in the grip of a post-pandemic acceleration of death due to burgeoning caseloads and an apparent change in viral behaviour. They have experience, foresight, materials and initiative, but the disease is overcoming the system and killing the citizens. The health purveyors are doing everything by the book, but the chapters are out-dated apparently.
What will we find in those sequences? How may we adapt our methods and materials to assist the families in India? When will those viral changes be adopted in other countries?
Pondering is excellent, but action is better.
The sequences will tell the truth and provide a footing to act. Please publish the sequences from May to August 2010.
Supporting / Related Sequences
. . . . India3725_2010_04_03 (
. . . . . . . . 117T,
. . . . . . . . syn167S,
. . . . . . . . 186P,
. . . . . . . . syn474C,
. . . . . . . . syn526S [SwedenMalmoe2_2010_05_07])
. . . . IndiaPune10604_2009_09 (
. . . . . . . . syn2N [UkrSumy797_2009_11_13_f,
. . . . . . . . . . . . . MongoliaJP5756_2009_10_15,
. . . . . . . .. . . . . SingON2416_2009_12_15],
. . . . . . . . syn50V [TexasJMS391_2009_12_23,
. . . . . . . . . . . . . . TexasJMS413_2009_02_03,
. . . . . . . . . . . . . . SouthCarolina02E3_2010_03_05],
. . . . . . . . syn178V (GTt) [NewHampshire02E3_2010_02_19 (GTa)],
. . . . . . . . 206S,
. . . . . . . . 296H,
. . . . . . . . syn348V [Yaroslavl_CHMV_2009_11_10_f with 225G,
. . . . . . . . . . . . . . Yakutsk_EAV_2009_11_18,
. . . . . . . . . . . . . . BZ_SaoPaulo53823_2009_08_01_f,
. . . . . . . . . . . . . . Eng662_2009_08],
. . . . . . . . syn485G [Nebraska 01_2010_01_28,
. . . . . . . . . . . . . . Orenburg2974_2009_11_16_xL,
. . . . . . . . . . . . . . NagasakiHA10_22_2010_03_01])
. . . . IndiaPune6196_2009_08 (
. . . . . . . . #12E,
. . . . . . . . syn2N [UkrSumy797_2009_11_13_f,
. . . . . . . . . . . . . MongoliaJP5756_2009_10_15,
. . . . . . . .. . . . . SingON2416_2009_12_15],
. . . . . . . . syn152I [NY6939_2009_12_11,
. . . . . . . . . . . . . . . tkOntarioFAV117_1C_2009_12_07,
. . . . . . . . . . . . . . . CalifVRDL115_2009_12_04,
. . . . . . . . . . . . . . . England1051_2009_12,
. . . . . . . . . . . . . . . England1050_2009_12,
. . . . . . . . . . . . . . . Scotland103_2009_12,
. . . . . . . . . . . . . . . England94800096_2009_11,
. . . . . . . . . . . . . . . ItalyAncona451_2009_11_27_f,
. . . . . . . . . . . . . . . NY6607_2009_11_24,
. . . . . . . . . . . . . . . CalifVRDL107_2009_11_15,
. . . . . . . . . . . . . . . CalifVRDL101_2009_11_05,
. . . . . . . . . . . . . . . DC_114_2009_11_04,
. . . . . . . . . . . . . . . Calif_SD35_2009_10_26,
. . . . . . . . . . . . . . . NY5447_2009_10_23,
. . . . . . . . . . . . . . . CalifVRDL84_2009_10_09,
. . . . . . . . . . . . . . . CalifVRDL87_2009_10_09,
. . . . . . . . . . . . . . . IndiaDhule9433_2009_08,
. . . . . . . . . . . . . . . SantoDomingoWR1057N_2009_07_02,
. . . . . . . . . . . . . . . SantoDomingoWR1058N_2009_07_02,
. . . . . . . . . . . . . . . SantoDomingoWR1059N_2009_06_30],
. . . . . . . . 206S,
. . . . . . . . 296H,
. . . . . . . . syn300P (CCt) [H5N1, H6N1, H7N3, H7N7],
. . . . . . . . . . . . . . . . . [Virginia24_2009_06_03 (CCt),
. . . . . . . . . . . . . . . . . NY0352_2009_12_27 (CCt),
. . . . . . . . . . . . . . . . . IllinoisAF2223_2009_12_18 (CCt),
. . . . . . . . . . . . . . . . . SingON2416_2009_12_15 (CCa),
. . . . . . . . . . . . . . . . . Vietnam2043_2009_12_01_TmX (CCa),
. . . . . . . . . . . . . . . . . HunanFur129_2010_01_13 (CCa),
. . . . . . . . . . . . . . . . . Slovenia5613_2009_12 (CCa),
. . . . . . . . . . . . . . . . . Minnesota40_2009_11_19 (CCa) w syn252V],
. . . . . . . . 342R,
. . . . . . . . syn348V [Yaroslavl_CHMV_2009_11_10_f with 225G,
. . . . . . . . . . . . . . Yakutsk_EAV_2009_11_18,
. . . . . . . . . . . . . . BZ_SaoPaulo53823_2009_08_01_f,
. . . . . . . . . . . . . . Eng662_2009_08],
. . . . . . . . syn355H [H2, H5N1, H6N1],
. . . . . . . . . . . . . . [GDLiwan1170_2010_03_14,
. . . . . . . . . . . . . . NY2963_2010_01_22
. . . . . . . . . . . . . .. . . . . . . . with 50E, 100N,
. . . . . . . . . . . . . . ItalyAncona508_2009_12_31
. . . . . . . . . . . . . .. . . . . . . . with syn181G,
. . . . . . . . . . . . . . Yamagata803_2009_12_21,
. . . . . . . . . . . . . . Astrakhan_CHRM_2009_11_24_xL_f,
. . . . . . . . . . . . . . MoscowOb_ZNF_2009_11_24_xL_f,
. . . . . . . . . . . . . . Ivanovo_STV1_2009_11_21
. . . . . . . . . . . . . .. . . . . . . . with 225G,
. . . . . . . . . . . . . . FloridaPensacola107_2009_11_12,
. . . . . . . . . . . . . . MoscowOb_STV_2009_11_09_f
. . . . . . . . . . . . . .. . . . . . . . with 225N,
. . . . . . . . . . . . . . swTaiwanTD4119B2_2009_11_04,
. . . . . . . . . . . . . . ArgentinaHNRG44_2009_06_30
. . . . . . . . . . . . . .. . . . . . . . with 71G,
. . . . . . . . . . . . . . ArgentinaHNRG39_2009_06_23
. . . . . . . . . . . . . .. . . . . . . . with 259T,
. . . . . . . . . . . . . . WiscD0589_2009_06_03
. . . . . . . . . . . . . .. . . . . . . . with syn178V])
. . . . IndiaDhule9433_2009_08 (
. . . . . . . . #12E,
. . . . . . . . syn2N [UkrSumy797_2009_11_13_f,
. . . . . . . . . . . . . MongoliaJP5756_2009_10_15,
. . . . . . . . . . . . . SingON2416_2009_12_15,
. . . . . . . . . . . . . IndiaPune10604_2009_09, et al],
. . . . . . . . syn152I [NY6939_2009_12_11,
. . . . . . . . . . . . . . . tkOntarioFAV117_1C_2009_12_07,
. . . . . . . . . . . . . . . CalifVRDL115_2009_12_04,
. . . . . . . . . . . . . . . England1051_2009_12,
. . . . . . . . . . . . . . . England1050_2009_12,
. . . . . . . . . . . . . . . Scotland103_2009_12,
. . . . . . . . . . . . . . . England94800096_2009_11,
. . . . . . . . . . . . . . . ItalyAncona451_2009_11_27_f,
. . . . . . . . . . . . . . . NY6607_2009_11_24,
. . . . . . . . . . . . . . . CalifVRDL107_2009_11_15,
. . . . . . . . . . . . . . . CalifVRDL101_2009_11_05,
. . . . . . . . . . . . . . . DC_114_2009_11_04,
. . . . . . . . . . . . . . . Calif_SD35_2009_10_26,
. . . . . . . . . . . . . . . NY5447_2009_10_23,
. . . . . . . . . . . . . . . CalifVRDL84_2009_10_09,
. . . . . . . . . . . . . . . CalifVRDL87_2009_10_09,
. . . . . . . . . . . . . . . IndiaPune6196_2009_08,
. . . . . . . . . . . . . . . SantoDomingoWR1057N_2009_07_02,
. . . . . . . . . . . . . . . SantoDomingoWR1058N_2009_07_02,
. . . . . . . . . . . . . . . SantoDomingoWR1059N_2009_06_30],
. . . . . . . . 176I,
. . . . . . . . 205W,
. . . . . . . . 206S,
. . . . . . . . 252L (cTG) [Maryland03_2010_01_13 (tTG),
. . . . . . . . . . . . . . . Guangdong2361_2009_11_25 (tTG)],
. . . . . . . . 296H,
. . . . . . . . syn348V [Yaroslavl_CHMV_2009_11_10_f with 225G,
. . . . . . . . . . . . . . Yakutsk_EAV_2009_11_18,
. . . . . . . . . . . . . . BZ_SaoPaulo53823_2009_08_01_f,
. . . . . . . . . . . . . . Eng662_2009_08],
. . . . . . . . syn386I [1918, Unique to PF11])
. . . . IndiaPune807_2009_07 (
. . . . . . . . #12E,
. . . . . . . . syn2N [UkrSumy797_2009_11_13_f ,
. . . . . . . . . . . . . MongoliaJP5756_2009_10_15,
. . . . . . . .. . . . . SingON2416_2009_12_15],
. . . . . . . . 100Q [Unique to PF11],
. . . . . . . . syn104L [CalifVRDL132_2009_12_30,
. . . . . . . . . . . . . . . Texas45122538_2009_09_12,
. . . . . . . . . . . . . . . WiscD0410_2009_09_24,
. . . . . . . . . . . . . . . WiscD1355_2009_09_21],
. . . . . . . . 206S,
. . . . . . . . 296H,
. . . . . . . . syn348V [Yaroslavl_CHMV_2009_11_10_f with 225G,
. . . . . . . . . . . . . . Yakutsk_EAV_2009_11_18,
. . . . . . . . . . . . . . BZ_SaoPaulo53823_2009_08_01_f,
. . . . . . . . . . . . . . Eng662_2009_08],
. . . . . . . . 461E [Unique to PF11]),
. . . . England1048_2009_12 (
. . . . . . . . 214R,
. . . . . . . . 225E,
. . . . . . . . 324I)
. . . . England1051_2009_12 (
. . . . . . . . syn10Y,
. . . . . . . . 35I,
. . . . . . . . syn152I [NY6939_2009_12_11,
. . . . . . . . . . . . . . . tkOntarioFAV117_1C_2009_12_07,
. . . . . . . . . . . . . . . CalifVRDL115_2009_12_04,
. . . . . . . . . . . . . . . England1050_2009_12,
. . . . . . . . . . . . . . . Scotland103_2009_12,
. . . . . . . . . . . . . . . England94800096_2009_11,
. . . . . . . . . . . . . . . ItalyAncona451_2009_11_27_f,
. . . . . . . . . . . . . . . NY6607_2009_11_24,
. . . . . . . . . . . . . . . CalifVRDL107_2009_11_15,
. . . . . . . . . . . . . . . CalifVRDL101_2009_11_05,
. . . . . . . . . . . . . . . DC_114_2009_11_04,
. . . . . . . . . . . . . . . Calif_SD35_2009_10_26,
. . . . . . . . . . . . . . . NY5447_2009_10_23,
. . . . . . . . . . . . . . . CalifVRDL84_2009_10_09,
. . . . . . . . . . . . . . . CalifVRDL87_2009_10_09,
. . . . . . . . . . . . . . . IndiaPune6196_2009_08,
. . . . . . . . . . . . . . . IndiaDhule9433_2009_08,
. . . . . . . . . . . . . . . SantoDomingoWR1057N_2009_07_02,
. . . . . . . . . . . . . . . SantoDomingoWR1058N_2009_07_02,
. . . . . . . . . . . . . . . SantoDomingoWR1059N_2009_06_30],
. . . . . . . . 206S,
. . . . . . . . syn219I,
. . . . . . . . syn254P,
. . . . . . . . syn276H,
. . . . . . . . syn456L,
. . . . . . . . 463V,
. . . . . . . . 502K [Ukraine],
. . . . . . . . 523A)
. . . . SouthCarolina02E3_2010_03_05 (
. . . . . . . . 25R [Utah42_2009_07_24 with 225G / 225N,
. . . . . . . . . . . Texas extensive (12),
. . . . . . . . . . . Afghanistan (2),
. . . . . . . . . . . Russia149_2009_11_01_xL],
. . . . . . . . syn50V [TexasJMS391_2009_12_23,
. . . . . . . . . . . . . TexasJMS413_2009_02_03,
. . . . . . . . . . . . . IndiaPune10604_2009_09],
. . . . . . . . 130E (GAa) [1918],
. . . . . . . . . . . . [Netherlands2243_2009_11_17_xL (GAg) mix
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . with 158E, 225G,
. . . . . . . . . . . . Iraq8531_2009_09_08_xL (GAa) with 131L,
. . . . . . . . . . . . Guangdong0872_2009_12_27 (GAa),
. . . . . . . . . . . . SingTLL52_2009_06_14 (GAa),
. . . . . . . . . . . . swAlbertaOTH_33_23_2009_05_03 (GAa)],
. . . . . . . . 206T)
. . . . TexasJMS413_2010_02_03 (
. . . . . . . . 25R,
. . . . . . . . syn50V,
. . . . . . . . syn84E)
. . . . TexasJMS391_2009_12_23 (
. . . . . . . . 25R,
. . . . . . . . syn50V,
. . . . . . . . syn84E,
. . . . . . . . syn374A)
. . . . NY2963_2010_01_22 (
. . . . . . . . 50E,
. . . . . . . . 100N,
. . . . . . . . syn270I,
. . . . . . . . syn291T,
. . . . . . . . syn355H,
. . . . . . . . 377K)
. . . . FloridaPensacola107_2009_11_12 (
. . . . . . . . 35I,
. . . . . . . . syn338G,
. . . . . . . . syn355H,
. . . . . . . . syn456L)
. . . . WiscD0589_2009_06_03 (
. . . . . . . . syn36L,
. . . . . . . . syn178V,
. . . . . . . . 193N,
. . . . . . . . syn355H)
. . . . Indiana21_2009_12_01 (
. . . . . . . . syn12A,
. . . . . . . . syn177L,
. . . . . . . . syn193S,
. . . . . . . . 212E mix,
. . . . . . . . 313K,
. . . . . . . . syn346G,
. . . . . . . . 359G,
. . . . . . . . 377K,
. . . . . . . . 494K)
. . . . IllinoisAF2223_2009_12_18 (
. . . . . . . . syn34N,
. . . . . . . . syn300P (CCt),
. . . . . . . . 377K,
. . . . . . . . HA truncated after aa386)
. . . . CalifVRDL107_2009_11_15 (
. . . . . . . . 35I,
. . . . . . . . 39N,
. . . . . . . . syn152I,
. . . . . . . . 206S,
. . . . . . . . syn219I,
. . . . . . . . syn276H,
. . . . . . . . syn456L,
. . . . . . . . 463V,
. . . . . . . . 523A)
. . . . CalifVRDL115_2009_12_04 (
. . . . . . . . 35I,
. . . . . . . . 77N,
. . . . . . . . syn152I,
. . . . . . . . 206S,
. . . . . . . . syn219I,
. . . . . . . . syn276H,
. . . . . . . . syn456L,
. . . . . . . . 463V,
. . . . . . . . 523A)
. . . . Malmoe2_2010_05_07 (
. . . . . . . . 89G,
. . . . . . . . syn108L [tn],
. . . . . . . . syn159N,
. . . . . . . . 206T,
. . . . . . . . 259T [ArgentinaHNRG39_2009_06_23
. . . . . . . . . . . . . . . . . . . . with syn355H],
. . . . . . . . syn280T [1918, WSN33],
. . . . . . . . syn526S [India3725_2010_04_03])
. . . . ItalyAncona508_2009_12_31 (
. . . . . . . . syn172K,
. . . . . . . . syn181G,
. . . . . . . . syn239P,
. . . . . . . . syn355H,
. . . . . . . . 373H)
. . . . GDLiwan1170_2010_03_14 (
. . . . . . . . 131P,
. . . . . . . . 202A,
. . . . . . . . 271T,
. . . . . . . . 298V,
. . . . . . . . syn355H,
. . . . . . . . 375F)
. . . . tkOntarioFAV117_1C_2009_12_07 (
. . . . . . . . 35I [H5N1],
. . . . . . . . syn55L,
. . . . . . . . syn152I,
. . . . . . . . 186P,
. . . . . . . . syn205G,
. . . . . . . . syn219I,
. . . . . . . . syn276H [1918, S5],
. . . . . . . . syn456L,
. . . . . . . . 463V,
. . . . . . . . syn486T,
. . . . . . . . 523A)
Please refer to additional studies for further genetic analyses, including the survey on amino acid revisions potentially related to Vaccine Escape. A hyper-morphic, TamiFlu-resistant sequence from the state of Washington in Spring 2010 has recently been profiled with similar zoonotic influences.
This analysis was fueled by puneri amti and funded with contributions from concerned families, including HOD, BMS, MJV and CSB.
* Rare, not Random
